ATF2 Rabbit pAb - diagbio | 戴格生物

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ATF2 Rabbit pAb

db9930

Product Name : ATF2 Rabbit pAb

Cat.No.: db9930

Synonyms : HB16; CREB2; TREB7; CREB-2; CRE-BP1

Application : WB, IHC, FC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]
Immunogen Recombinant protein of human ATF2
Gene ID 1386
Swiss Prot P16951
Synonyms HB16; CREB2; TREB7; CREB-2; CRE-BP1
Reactivity Human, Mouse, Rat
Application WB, IHC, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
FC: 1:20
IP: 1:20
Calculated MW 55 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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