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Glutathione Peroxidase 3/GPx-3 Rabbit pAb
Alternate Text

Product Name : Glutathione Peroxidase 3/GPx-3 Rabbit pAb

Cat.No.: db9592

Synonyms : GPx; EGPx; GSHPx-3; GSHPx-P; AA960521

Application : WB, IHC

Reactivity : Mouse, Rat

Host species : Rabbit

  • Background The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is secreted and is highly expressed in mouse kidney, which appears to be the major source of the enzyme in plasma. It has a role in mouse organogenesis, and dysregulation of this isozyme has been associated with obesity-related metabolic complications, platelet-dependent thrombosis, colitis-associated carcinoma, and thermosensitive phenotype. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2016]
  • Immunogen Recombinant protein of mouse Glutathione Peroxidase 3/GPx-3
  • Gene ID 14778
  • Swiss Prot P23764
  • Synonyms GPx; EGPx; GSHPx-3; GSHPx-P; AA960521
  • Reactivity Mouse, Rat
  • Application WB, IHC
  • Recommended dilution WB: 1:1000
    IHC: 1:50
  • Calculated MW 25 kDa
  • Observed MW 25 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.