IL-6R Rabbit pAb - diagbio | 戴格生物

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IL-6R Rabbit pAb

db9521

Datasheet

Product Name : IL-6R Rabbit pAb

Cat.No.: db9521

Synonyms : IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1

Application : WB, FC, IP

Reactivity : Human

Host species : Rabbit

Background This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
Immunogen Recombinant protein of human IL-6R
Gene ID 3570
Swiss Prot P08887
Synonyms IL6Q; gp80; CD126; IL6RA; IL6RQ; IL-6RA; IL-6R-1
Reactivity Human
Application WB, FC, IP
Recommended dilution WB: 1:1000
FC: 1:20
IP: 1:20
Calculated MW 52 kDa
Observed MW 40-80 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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