IL-10 Rabbit pAb - diagbio | 戴格生物

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IL-10 Rabbit pAb

db9419

Datasheet

Product Name : IL-10 Rabbit pAb

Cat.No.: db9419

Synonyms : CSIF; TGIF; GVHDS; IL-10; IL10A

Application : WB, ICC/IF, FC

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
Immunogen A synthetic peptide of human IL-10
Gene ID 3586
Swiss Prot P22301
Synonyms CSIF; TGIF; GVHDS; IL-10; IL10A
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:50
FC: 1:20-1:100
Calculated MW 21 kDa
Observed MW 17 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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