c-Kit Rabbit pAb - diagbio | 戴格生物

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c-Kit Rabbit pAb

db9066

Datasheet

Product Name : c-Kit Rabbit pAb

Cat.No.: db9066

Synonyms : PBT; SCFR; C-Kit; CD117; MASTC

Application : WB, IHC

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2020]
Immunogen Recombinant protein of human c-Kit
Gene ID 3815
Swiss Prot P10721
Synonyms PBT; SCFR; C-Kit; CD117; MASTC
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:500
Calculated MW 110 kDa
Observed MW 120-145 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息

Package Price (RMB)
20μL 598
50μL 998
100μL 1798
货期：现货