HLA-DR Rabbit pAb - diagbio | 戴格生物

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HLA-DR Rabbit pAb

db879

Product Name : HLA-DR Rabbit pAb

Cat.No.: db879

Synonyms : HLA-DRA1

Application : WB, IHC, ICC/IF, FC

Reactivity : Human, Rat

Host species : Rabbit

Background HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human HLA-DR
Gene ID 3122
Swiss Prot P01903
Synonyms HLA-DRA1
Reactivity Human, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:2000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
Calculated MW 29 kDa
Observed MW 29 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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