Bax Rabbit pAb - diagbio | 戴格生物

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Bax Rabbit pAb

db819

Product Name : Bax Rabbit pAb

Cat.No.: db819

Synonyms : BCL2L4

Application : WB, IHC, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Bax
Gene ID 581
Swiss Prot Q07812
Synonyms BCL2L4
Reactivity Human, Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:20-1:500
IP: 1:20
Calculated MW 21 kDa
Observed MW 20 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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