IL-12A Rabbit pAb - diagbio | 戴格生物

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IL-12A Rabbit pAb

db8113

Product Name : IL-12A Rabbit pAb

Cat.No.: db8113

Synonyms : P35; CLMF; NFSK; NKSF1; IL-12A

Application : WB, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human IL-12A
Gene ID 3592
Swiss Prot P29459
Synonyms P35; CLMF; NFSK; NKSF1; IL-12A
Reactivity Human, Mouse, Rat
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 25 kDa
Observed MW 35 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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