Phospho-eIF4E (Ser209) Rabbit pAb - diagbio | 戴格生物

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Phospho-eIF4E (Ser209) Rabbit pAb

db8101

Product Name : Phospho-eIF4E (Ser209) Rabbit pAb

Cat.No.: db8101

Synonyms : CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1

Application : WB, IHC, ICC/IF, IP

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser209 of human eIF4E
Gene ID 1977
Swiss Prot P06730
Synonyms CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:1000-1:10000
IHC: 1:50
ICC/IF: 1:100
IP: 1:20
Calculated MW 25 kDa
Observed MW 25 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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