Product Name :
CD13 Rabbit pAb
Cat.No.:
db7863
Synonyms :
APN; CD13; LAP1; P150; PEPN; GP150
Application :
WB, IHC, ICC/IF, IP
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human CD13
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Gene ID
290
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Swiss Prot
P15144
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Synonyms
APN; CD13; LAP1; P150; PEPN; GP150
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, ICC/IF, IP
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Recommended dilution
WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
IP: 1:20
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Calculated MW
110 kDa
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Observed MW
160 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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