Product Name :
GAPDH Rabbit pAb
Cat.No.:
db7662
Synonyms :
G3PD; GAPD; HEL-S-162eP
Application :
WB, IHC, ICC/IF, FC
Reactivity :
Human, Mouse, Rat, Monkey, Chicken, Dog
Host species :
Rabbit
-
Background
This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
-
Immunogen
Recombinant protein of human GAPDH
-
Gene ID
2597
-
Swiss Prot
P04406
-
Synonyms
G3PD; GAPD; HEL-S-162eP
-
Reactivity
Human, Mouse, Rat, Monkey, Chicken, Dog
-
Application
WB, IHC, ICC/IF, FC
-
Recommended dilution
WB: 1:2000
IHC: 1:100
ICC/IF: 1:50
FC: 1:50
-
Calculated MW
36 kDa
-
Observed MW
36 kDa
-
Host species
Rabbit
-
Clonality
Polyclonal
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
-
发表于
Toxicology letters
-
2022年
样本种属:
Human
应用:
WB
订购信息
-
Package
Price (RMB)
-
20μL
598
-
100μL
1000
-
500μL
4000
-
1mL
7200
- 货期:现货
For research use only. Not intended for diagnostic.