CD8 alpha Rabbit pAb - diagbio | 戴格生物

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CD8 alpha Rabbit pAb

db7449

Product Name : CD8 alpha Rabbit pAb

Cat.No.: db7449

Synonyms : CD8; p32; Leu2

Application : IHC, FC, IP

Reactivity : Human

Host species : Rabbit

Background The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Immunogen Recombinant protein of human CD8 alpha
Gene ID 925
Swiss Prot P01732
Synonyms CD8; p32; Leu2
Reactivity Human
Application IHC, FC, IP
Recommended dilution IHC: 1:100
FC: 1:50
IP: 1:20
Calculated MW 26 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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