Ephrin receptor A2 Rabbit pAb - diagbio | 戴格生物

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Ephrin receptor A2 Rabbit pAb

db7367

Product Name : Ephrin receptor A2 Rabbit pAb

Cat.No.: db7367

Synonyms : Eck; Myk2; Sek2; Sek-2; AW545284

Application : WB, ICC/IF, FC, IP

Reactivity : Mouse, Rat

Host species : Rabbit

Background Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 signaling pathway.
Immunogen Recombinant protein of mouse Ephrin receptor A2
Gene ID 13836
Swiss Prot Q03145
Synonyms Eck; Myk2; Sek2; Sek-2; AW545284
Reactivity Mouse, Rat
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20
FC: 1:20
IP: 1:20
Calculated MW 109 kDa
Observed MW 125 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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