DR5 Rabbit pAb - diagbio | 戴格生物

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DR5 Rabbit pAb

db7259

Product Name : DR5 Rabbit pAb

Cat.No.: db7259

Synonyms : DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5

Application : WB, IHC, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
Immunogen A synthetic peptide of human DR5
Gene ID 8795
Swiss Prot O14763
Synonyms DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5
Reactivity Human
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
IP: 1:20
Calculated MW 49 kDa
Observed MW 40,49 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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