Product Name :
ERK1/2 (9A4) Mouse mAb
Cat.No.:
db6621
Synonyms :
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
Application :
WB, IHC-P
Reactivity :
Human, Rat, Mouse
Host species :
Mouse
-
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
-
Immunogen
Synthetic peptide conjugated to KLH
-
Gene ID
5594
5595
-
Swiss Prot
P27361
P28482
-
Synonyms
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
-
Reactivity
Human, Rat, Mouse
-
Application
WB, IHC-P
-
Recommended dilution
WB: 1:500-1:1000
IHC: 1:50-1:100
-
Calculated MW
44,42 kDa
-
Observed MW
44,42 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
9A4-2D4-7A3
-
Isotype
IgG1
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
-
Immunohistochemistry analysis of paraffin-embedded Human Breast Carcinoma using ERK1/2 (9A4) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Western blot analysis of ERK1/2 (9A4) in Hela, C6 lysates using ERK1/2 (9A4) antibody
-
Western blot analysis of ERK1/2 (9A4) in mouse brain, rat brain , Hela lysates using ERK1/2 (9A4) antibody
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.