Product Name : TATA Box Binding Protein (10C1) Mouse mAb
Cat.No.: db6620
Synonyms : TBP; GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit
Application : IHC-P
Reactivity : Human, Rat, Mouse
Host species : Mouse
- Background General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed/2374612, PubMed/2363050, PubMed/2194289, PubMed/9836642, PubMed/27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed/2374612, PubMed/2363050, PubMed/2194289, PubMed/9836642, PubMed/27193682). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed/26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription (PubMed/15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
- Immunogen Purified recombinant protein expressed in E.coli
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Gene ID
6908
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Swiss Prot
P20226
- Synonyms TBP; GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit
- Reactivity Human, Rat, Mouse
- Application IHC-P
- Recommended dilution IHC: 1:50-1:100
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 10C1-4F6-4B7
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
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Immunohistochemistry analysis of paraffin-embedded Human Breast Carcinoma using TATA Box Binding Protein (10C1) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
