AMPK beta 1 Mouse mAb - diagbio | 戴格生物

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AMPK beta 1 Mouse mAb

db6601

Product Name : AMPK beta 1 Mouse mAb

Cat.No.: db6601

Synonyms : 5''-AMP-activated protein kinase subunit beta-1; AMP-activated; noncatalytic; beta-1; AMPK; AMPK beta 1 chain; AMPK subunit beta-1; AMPK-BETA-1; AMPKb; HAMPKb; PRKAB1

Application : WB

Reactivity : Human

Host species : Mouse

Background Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes/ inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Immunogen Recombinant Protein of AMPKβ1
Gene ID 5564
Swiss Prot Q9Y478
Synonyms 5''-AMP-activated protein kinase subunit beta-1; AMP-activated; noncatalytic; beta-1; AMPK; AMPK beta 1 chain; AMPK subunit beta-1; AMPK-BETA-1; AMPKb; HAMPKb; PRKAB1
Reactivity Human
Application WB
Recommended dilution WB: 1:500-1:1000
Calculated MW 30 kDa
Observed MW 38 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 2F2-4F9
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of AMPKβ1 in Hela, COS7 lysates using AMPK beta 1 antibody.

订购信息

Package Price (RMB)
50μL 1398
100μL 2398
货期：现货