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Bcl2 (9A4) Mouse mAb
db6598
Datasheet
- Background Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed/17418785).
- Immunogen Synthetic peptide conjugated to KLH
-
Gene ID
596
-
Swiss Prot
P10415
- Synonyms BCL2; Apoptosis regulator Bcl-2
- Reactivity Human, Rat, Mouse
- Application WB
- Recommended dilution WB: 1:500-1:1000
- Calculated MW 26 kDa
- Observed MW 26 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 9A4-8B3-6E8
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of BCL2(2C12) in THP-1 lysates using BCL2 mouse Monoclonal Anbitoy(2C12) antibody.
订购信息
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
