Product Name :
ERK1/2 (1B4) Mouse mAb
Cat.No.:
db6570
Synonyms :
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
Application :
WB, IHC-P
Reactivity :
Human, Rat, Mouse
Host species :
Mouse
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Background
erine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
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Immunogen
Synthetic peptide conjugated to KLH
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Gene ID
5594
5595
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Swiss Prot
P27361
P28482
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Synonyms
MAPK3; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; MAPK1; ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK
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Reactivity
Human, Rat, Mouse
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Application
WB, IHC-P
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Recommended dilution
WB: 1:500-1000
IHC: 1:50-100
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Calculated MW
44,42 kDa
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Observed MW
44,42 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
1B4-6A3-10A5
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of ERK1/2 (1B4)in Hela lysates, mouse Brain lysates, rat Brain lysates using ERK1/2 antibody.
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Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using ERK1/2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using ERK1/2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.