Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse mAb - diagbio | 戴格生物

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Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse mAb

db6548

Product Name : Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Mouse mAb

Cat.No.: db6548

Synonyms : MAPK1/MAPK3

Application : IHC-P

Reactivity : Human, Rat, Mouse

Host species : Mouse

Background Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Immunogen Synthetic peptide conjugated to KLH
Gene ID 5594
5595
Swiss Prot P27361
P28482
Synonyms MAPK1/MAPK3
Reactivity Human, Rat, Mouse
Application IHC-P
Recommended dilution IHC: 1:50-1:100
Host species Mouse
Clonality Monoclonal
Clonality No. 1H4-6D7-9D8
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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