Caspase-3 (5H3) Mouse mAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Caspase-3 (5H3) Mouse mAb

db6539

Product Name : Caspase-3 (5H3) Mouse mAb

Cat.No.: db6539

Synonyms : CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1

Application : IHC-P

Reactivity : Human, Rat, Mouse

Host species : Mouse

Background Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Immunogen Synthetic peptide conjugated to KLH
Gene ID 836
Swiss Prot P42574
Synonyms CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Reactivity Human, Rat, Mouse
Application IHC-P
Recommended dilution IHC: 1:50-1:100
Host species Mouse
Clonality Monoclonal
Clonality No. 5H3-3H7-7G2
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded Human Skin Tissue using Caspase 3 (5H3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using Caspase 3 (5H3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded mouse Liver Tissue using Caspase3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

订购信息