IKB beta (5H3) Mouse mAb - diagbio | 戴格生物

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IKB beta (5H3) Mouse mAb

db6531

Product Name : IKB beta (5H3) Mouse mAb

Cat.No.: db6531

Synonyms : I kappa b beta; IKB b; NFKBib; TRIP9

Application : IHC-P

Reactivity : Human, Rat, Mouse

Host species : Mouse

Background Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
Immunogen Purified recombinant protein expressed in E.coli
Gene ID 4793
Swiss Prot Q15653
Synonyms I kappa b beta; IKB b; NFKBib; TRIP9
Reactivity Human, Rat, Mouse
Application IHC-P
Recommended dilution IHC: 1:50-1:100
Calculated MW 48 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 5H3-4C7-1H6
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma using IKB beta (5H3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemical analysis of paraffin-embedded Human tonsils using IKB beta (5H3) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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