Bcl2 (3H5) Mouse mAb - diagbio | 戴格生物

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Bcl2 (3H5) Mouse mAb

db6522

Datasheet

Product Name : Bcl2 (3H5) Mouse mAb

Cat.No.: db6522

Synonyms : BCL2; Apoptosis regulator Bcl-2

Application : ICC/IF, WB, IHC-P

Reactivity : Human, Chicken

Host species : Mouse

Background Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed/17418785).
Immunogen Synthetic Peptide of Bcl-2
Gene ID 596
Swiss Prot P10415
Synonyms BCL2; Apoptosis regulator Bcl-2
Reactivity Human, Chicken
Application ICC/IF, WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Calculated MW 26 kDa
Observed MW 26 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 3H5-2H8-1H5
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using Bcl2 (3H5) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of Bcl2 (3H5) in chicken lysates using Bcl2 (3H5) antibody
Western blot analysis of Bcl2 in Human breast cancer cell line MCF-7(A), MDAMB231(B) and Cal51(C) using Bcl2 antibody.
Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Bcl2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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