TriMethyl-Histone H3 (Lys79) (6A6) Mouse mAb
Product Name :
TriMethyl-Histone H3 (Lys79) (6A6) Mouse mAb
Cat.No.:
db6447
Synonyms :
H3K79me3; H3 histone; HIST1H3A; Histone cluster 1; H3a
Application :
WB, IHC-F, IHC-P, ICC/IF, IP
Reactivity :
Human, Mouse, Rat
Host species :
Mouse
-
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.MiscellaneousThis histone is only present in mammals and is enriched in acetylation of Lys-15 and dimethylation of Lys-10 (H3K9me2).
-
Immunogen
Synthetic Peptide of Histone H3 (Tri Methyl Lys79)
-
Gene ID
8290
-
Swiss Prot
P68431
-
Synonyms
H3K79me3; H3 histone; HIST1H3A; Histone cluster 1; H3a
-
Reactivity
Human, Mouse, Rat
-
Application
WB, IHC-F, IHC-P, ICC/IF, IP
-
Recommended dilution
WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
IP: 1:20
-
Calculated MW
15 kDa
-
Observed MW
15 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
6A6-5D1-10A10
-
Isotype
IgG1
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
-
Western blot analysis of TriMethyl-Histone H3 (Lys79) in Hela, rat Testis , Raw264.7 lysates using Histone H3 (tri methyl K79) (3G3) antibody.
-
Immunoprecipitation analysis of TriMethyl-Histone H3 (Lys79) (6A6) in Hela lysates using TriMethyl-Histone H3 (Lys79) (6A6) antibody
-
Western blot analysis of TriMethyl-Histone H3 (Lys79) (6A6) in T47D, COS7 and C6 lysates using TriMethyl-Histone H3 (Lys79) antibody.
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.