CD45 (8C1) Mouse mAb - diagbio | 戴格生物

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CD45 (8C1) Mouse mAb

db6424

Product Name : CD45 (8C1) Mouse mAb

Cat.No.: db6424

Synonyms : GP180; L CA; CD45 antigen

Application : ICC/IF, WB, IHC-P

Reactivity : Human

Host species : Mouse

Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Immunogen Synthetic Peptide of CD45
Gene ID 19264
Swiss Prot P06800
Synonyms GP180; L CA; CD45 antigen
Reactivity Human
Application ICC/IF, WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
Calculated MW 145 kDa
Observed MW 145 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 8C1-9B8-2H1
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunofluorescence analysis of CD45 (8C1) in Human livercancer tissue using CD45 (8C1) antibody(red),and DAPI (blue).
Immunohistochemical analysis of paraffin-embedded Human tonsils using CD45 (8C1) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Negative control was used by secondary antibody only.
Western blot analysis of CD45 (8C1) in Jurkat lysates using CD45 (8C1) antibody.

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