Product Name :
GSK3 beta Mouse mAb
Cat.No.:
db6410
Synonyms :
GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
Application :
WB, IHC-P, FC
Reactivity :
Human, Mouse, Rat
Host species :
Mouse
-
Background
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
Immunogen
Purified recombinant fragment of human GSK3B (AA/ 2-159) expressed in E. Coli
-
Gene ID
2932
-
Swiss Prot
P49841
-
Synonyms
GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
-
Reactivity
Human, Mouse, Rat
-
Application
WB, IHC-P, FC
-
Recommended dilution
WB: 1:500-1:1000
IHC: 1:50-1:100
FC: 1:50-1:100
-
Calculated MW
47 kDa
-
Observed MW
47 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
7D8A6
-
Isotype
IgG1
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
-
Flow Cytometry analysis of NIH/3T3 cells stained with GSK3B antibody (green) and negative control (red).
-
Immunohistochemistry analysis of paraffin-embedded rectum cancer tissues using GSK3B antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Immunohistochemistry analysis of paraffin-embedded esophageal cancer tissues using GSK3B antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
-
Western blot analysis of GSK3B antibody in Hela, 3T3, C6, rat Brain lysates using GSK3B antibody.
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.