CD45 Mouse mAb - diagbio | 戴格生物

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CD45 Mouse mAb

db6409

Product Name : CD45 Mouse mAb

Cat.No.: db6409

Synonyms : PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45

Application : WB, IHC-P

Reactivity : Human, Mouse

Host species : Mouse

Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Immunogen Purified recombinant fragment of human PTPRC (AA/ 928-989) expressed in E. Coli
Gene ID 5788
Swiss Prot P08575
Synonyms PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
Reactivity Human, Mouse
Application WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
Calculated MW 147 kDa
Observed MW 180-240 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 5D3A3
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Immunohistochemistry analysis of paraffin-embedded breast cancer tissues using PTPRC antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Immunohistochemistry analysis of paraffin-embedded esophageal cancer tissues using PTPRC antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of PTPRC antibody in Ramos, Raw264.7 lysates using PTPRC antibody.

订购信息

Package Price (RMB)
50μL 1398
100μL 2398
货期：现货