Synaptophysin (10C8) Mouse mAb - diagbio | 戴格生物

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Synaptophysin (10C8) Mouse mAb

db6404

Product Name : Synaptophysin (10C8) Mouse mAb

Cat.No.: db6404

Synonyms : SYP; Synaptophysin; Major synaptic vesicle protein p38

Application : WB, IHC-P

Reactivity : Human, Mouse, Rat

Host species : Mouse

Background Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex.
Immunogen Purified recombinant fragment of SYP expressed in E. Coli
Gene ID 6855
Swiss Prot P08247
Synonyms SYP; Synaptophysin; Major synaptic vesicle protein p38
Reactivity Human, Mouse, Rat
Application WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
Calculated MW 34 kDa
Observed MW 34 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 10C8-10F9-9H9
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of Synaptophysin (10C8) in rat brain lysates using Synaptophysin (10C8) antibody.
Immunohistochemical analysis of paraffin-embedded Human tonsils using Synaptophysin (10C8) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Western blot analysis of Synaptophysin (10C8) in rat Brain, rat Hippocampus, Hela, 3T3 lysates using Synaptophysin (10C8) antibody

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