Bid (3C5) Mouse mAb - diagbio | 戴格生物

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Bid (3C5) Mouse mAb

db6393

Product Name : Bid (3C5) Mouse mAb

Cat.No.: db6393

Synonyms : FP497; MGC15319; MGC42355; BID

Application : WB, ICC/IF, FC

Reactivity : Human

Host species : Mouse

Background This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.Tissue specificity/ Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level)
Immunogen Purified recombinant fragment of human BID expressed in E. Coli
Gene ID 637
Swiss Prot P55957
Synonyms FP497; MGC15319; MGC42355; BID
Reactivity Human
Application WB, ICC/IF, FC
Recommended dilution WB: 1:500-1:1000
ICC/IF: 1:50-1:200
FC: 1:50-1:100
Calculated MW 22 kDa
Observed MW 22 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 3C5-E5-C3
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of Bid in 293T, Jurkat and A431 lysates using Bid antibody.
Immunocytochemistry analysis of Bid (3C5) in HeLa using Bid antibody.

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