CD44 (2H12) Mouse mAb - diagbio | 戴格生物

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CD44 (2H12) Mouse mAb

db6337

Product Name : CD44 (2H12) Mouse mAb

Cat.No.: db6337

Synonyms : IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; CD44

Application : WB, IP, ICC/IF, IHC-F, IHC-P

Reactivity : Human

Host species : Mouse

Background Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Immunogen Purified recombinant human CD44 protein fragments expressed in E.coli
Gene ID 960
Swiss Prot P16070
Synonyms IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1; CDW44; CSPG8; HCELL; HUTCH-I; ECMR-III; CD44
Reactivity Human
Application WB, IP, ICC/IF, IHC-F, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
ICC/IF: 1:50-1:200
IP: 1:20
Calculated MW 82 kDa
Observed MW 82 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 2H12-E7-G7
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of CD44 in HUVEC lysates using CD44 antibody.
Immunoprecipitation analysis of CD44 (2H12) in Hela lysates using CD44 antibody.
Immunofluorescence analysis of CD44 (2H12) in HeLa cells using CD44 antibody(green),and DAPI (blue)
Immunohistochemistry analysis of paraffin-embedded Human tonsils using CD44 (2H12) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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