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S100B (5G3) Mouse mAb
db6293
Datasheet
- Background Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
- Immunogen Human S100B synthetic peptide conjugated to KLH
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Gene ID
6285
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Swiss Prot
P04271
- Synonyms NEF; S100; S100-B; S100beta
- Reactivity Rat
- Application WB
- Recommended dilution WB: 1:500-1:1000
- Calculated MW 11 kDa
- Observed MW 11 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 5G3-C11
- Isotype IgG2b
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of S100B (5G3) in rat Brain lysates using S100B antibody.
订购信息
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
