eIF4E (8C8) Mouse mAb - diagbio | 戴格生物

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eIF4E (8C8) Mouse mAb

db6264

Product Name : eIF4E (8C8) Mouse mAb

Cat.No.: db6264

Synonyms : EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Mouse

Background Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1. Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
Immunogen Purified recombinant human eif4e protein expressed in E.coli
Gene ID 1977
Swiss Prot P06730
Synonyms EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding protein
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:500-1:1000
Calculated MW 25 kDa
Observed MW 25 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 8C8-C10-C12
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of eIF4E in MDA-MB-468, ZR751, MCF-7, T47D and CHO-K1 lysates using eIF4E antibody.
Western blot analysis of eIF4E (8C8) in Jurkat, Hela, MCF-7, K562, C6, 3T3, PC-12, HepG2, CHO-K1, Raji, Raw264.7 and Ramos lysates using eIF4E antibody.

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