Caspase-9 (1D1) Mouse mAb
Product Name :
Caspase-9 (1D1) Mouse mAb
Cat.No.:
db6217
Synonyms :
CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
Application :
WB
Reactivity :
Human
Host species :
Mouse
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Background
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
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Immunogen
Purified recombinant human Caspase-9 protein fragments expressed in E.coli
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Gene ID
842
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Swiss Prot
P55211
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Synonyms
CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:500-1:1000
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Calculated MW
46 kDa
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Observed MW
49,37 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
1D1-F2-E9
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of Caspase9 in A549, MCF-7, Jurkat, K562 and Hela lysates using Caspase9 antibody.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.