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Caspase-9 (1D1) Mouse mAb

Product Name : Caspase-9 (1D1) Mouse mAb

Cat.No.: db6217

Synonyms : CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6

Application : WB

Reactivity : Human

Host species : Mouse

  • Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
  • Immunogen Purified recombinant human Caspase-9 protein fragments expressed in E.coli
  • Gene ID 842
  • Swiss Prot P55211
  • Synonyms CASP9; MCH6; APAF3; APAF-3; PPP1R56; ICE-LAP6
  • Reactivity Human
  • Application WB
  • Recommended dilution WB: 1:500-1:1000
  • Calculated MW 46 kDa
  • Observed MW 49,37 kDa
  • Host species Mouse
  • Clonality Monoclonal
  • Clonality No. 1D1-F2-E9
  • Isotype IgG1
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
  • Western blot analysis of Caspase9 in A549, MCF-7, Jurkat, K562 and Hela lysates using Caspase9 antibody.
订购信息
  • Package Price (RMB)
  • 50μL 1398
  • 100μL 2398
  • 货期:现货
For research use only. Not intended for diagnostic.