Product Name :
Bax (2B12) Mouse mAb
Cat.No.:
db6205
Synonyms :
Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Application :
WB
Reactivity :
Human, Monkey
Host species :
Mouse
-
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
-
Immunogen
Purified recombinant human Bax protein fragments expressed in E.coli
-
Gene ID
581
-
Swiss Prot
Q07812
-
Synonyms
Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
-
Reactivity
Human, Monkey
-
Application
WB
-
Recommended dilution
WB: 1:500-1:1000
-
Calculated MW
21 kDa
-
Observed MW
21 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
2B12-G6-H6
-
Isotype
IgG2a
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% Glycerol(pH 7.3), 0.02% sodium azide and 0.5% BSA . Stable for 12 months from date of receipt.
-
Western blot analysis of Bax in COS7, Raji, CEM and Hela lysates using Bax antibody.
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.