CD31 (5E2) Mouse mAb - diagbio | 戴格生物

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CD31 (5E2) Mouse mAb

db6193

Product Name : CD31 (5E2) Mouse mAb

Cat.No.: db6193

Synonyms : Cd31;Pecam;C85791;PECAM-1

Application : WB, IHC-P

Reactivity : Human

Host species : Mouse

Background PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.
Immunogen Purified recombinant human CD31 protein fragments expressed in E.coli
Gene ID 5175
Swiss Prot P16284
Synonyms Cd31;Pecam;C85791;PECAM-1
Reactivity Human
Application WB, IHC-P
Recommended dilution WB: 1:500-1:1000
IHC: 1:50-1:100
Calculated MW 83 kDa
Observed MW 130 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 5E2-G4-G10
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of CD31 in THP-1 lysates using CD31 antibody.
Immunohistochemistry analysis of paraffin-embedded Human tonsils using CD31/PECAM1 (5E2) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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