FAK (3D8) Mouse mAb - diagbio | 戴格生物

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FAK (3D8) Mouse mAb

db6186

Datasheet

Product Name : FAK (3D8) Mouse mAb

Cat.No.: db6186

Synonyms : FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK

Application : WB, ICC/IF, IP

Reactivity : Human

Host species : Mouse

Background Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Immunogen Purified recombinant human FAK protein fragments expressed in E.coli
Gene ID 5747
Swiss Prot Q05397
Synonyms FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
Reactivity Human
Application WB, ICC/IF, IP
Recommended dilution WB: 1:500-1:1000
ICC/IF: 1:50-1:200
IP: 1:20
Calculated MW 119 kDa
Observed MW 125 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. 3D8-H11-E12
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.

Western blot analysis of FAK in COS7, HUVEC, A549 and Hela lysates using FAK antibody.
Immunofluorescence analysis of FAK (3D8) in Hela using FAK antibody.
Immunoprecipitation analysis of FAK (3D8) in Hela lysates using FAK antibody.

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