Product Name :
p38 (5A1) Mouse mAb
Cat.No.:
db6168
Synonyms :
RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; MAPK14
Application :
WB
Reactivity :
Human, Mouse, Rat, Monkey
Host species :
Mouse
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Background
Responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. Plays a critical role in the production of some cytokines, for example IL-6. May play a role in stabilization of EPO mRNA during hypoxic stress. Isoform Mxi2 activation is stimulated by mitogens and oxidative stress and only poorly phosphorylates ELK1 and ATF2. Isoform Exip may play a role in the early onset of apoptosis.
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Immunogen
Purified recombinant human P38 MAPK Pprotein fragments expressed in E.coli
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Gene ID
1432
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Swiss Prot
Q16539
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Synonyms
RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA; MAPK14
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Reactivity
Human, Mouse, Rat, Monkey
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Application
WB
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Recommended dilution
WB: 1:500-1:1000
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Calculated MW
41 kDa
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Observed MW
41 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
5A1-C5-F11
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of p38 (5A1) in C2C12, PC-12, HepG2, COS7, C6, 3T3 and Hela lysates using p38 MAPK antibody.
订购信息
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Package
Price (RMB)
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.