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CRK (3H7) Mouse mAb
db6158
Datasheet
- Background The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
- Immunogen Purified recombinant human CrkII protein fragments expressed in E.coli
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Gene ID
1398
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Swiss Prot
P46108
- Synonyms p38; CRKII
- Reactivity Human
- Application WB
- Recommended dilution WB: 1:500-1:1000
- Calculated MW 34 kDa
- Observed MW 34 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 3H7-E5-H8
- Isotype IgG2b
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of CrkII in Lncap, A431, MCF-7 and HT-1080 lysates using CrkII antibody.
订购信息
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
