Product Name :
ERK1/2 (4A4) Mouse mAb
Cat.No.:
db6122
Synonyms :
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
Application :
WB
Reactivity :
Human, Mouse, Rat
Host species :
Mouse
-
Background
Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
-
Immunogen
Human p44 MAPK (Erk1) synthetic peptide conjugated to KLH
-
Gene ID
5595
5594
-
Swiss Prot
P27361
P28482
-
Synonyms
ERK; p38; p40; p41; ERK2; ERT1; ERK-2; MAPK2; PRKM1; PRKM2; P42MAPK; p41mapk; p42-MAPK; ERK1; ERT2; ERK-1; PRKM3; P44ERK1; P44MAPK; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK
-
Reactivity
Human, Mouse, Rat
-
Application
WB
-
Recommended dilution
WB: 1:500-1:1000
-
Calculated MW
44,42 kDa
-
Observed MW
42,44 kDa
-
Host species
Mouse
-
Clonality
Monoclonal
-
Clonality No.
4A4-G4-F6
-
Isotype
IgG1
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
-
Western blot analysis of ERK1/2 (4A4) in EGFtreated A549 , PDGFtreated 3T3 and TPAtreated 3T3 lysates using ERK1/2 (4A4) antibody.
订购信息
-
Package
Price (RMB)
-
50μL
1398
-
100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.