Product Name : KDM1A (1E5) Mouse mAb
Cat.No.: db6007
Synonyms : KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
Application : WB, ICC/IF, IP
Reactivity : Human, Monkey
Host species : Mouse
- Background Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes.
- Immunogen Purified recombinant human KDM1/LSD1 protein fragments expressed in E.coli
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Gene ID
23028
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Swiss Prot
O60341
- Synonyms KDM1A; AOF2; KDM1; KIAA0601; LSD1; Lysine-specific histone demethylase 1A; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2
- Reactivity Human, Monkey
- Application WB, ICC/IF, IP
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Recommended dilution
WB: 1:500-1:1000
ICC/IF: 1:50-1:200
IP: 1:20 - Calculated MW 93 kDa
- Observed MW 110 kDa
- Host species Mouse
- Clonality Monoclonal
- Clonality No. 1E5-H2
- Isotype IgG1
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in PBS, 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. Stable for 12 months from date of receipt.
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Western blot analysis of KDM1/LSD1 in Hela, HCT116 and COS7 lysates using KDM1/LSD1 antibody. -
Immunocytochemistry analysis of KDM1A (1E5) in HeLa using KDM1/LSD1 antibody. -
Immunoprecipitation analysis of KDM1A (1E5) in Hela lysates using KDM1/LSD1 antibody.
- Package Price (RMB)
- 50μL 1398
- 100μL 2398
- 货期：现货
