IL-2 Receptor alpha Rabbit pAb
Product Name :
IL-2 Receptor alpha Rabbit pAb
Cat.No.:
db5752
Synonyms :
p55; CD25; IL2R; IMD41; TCGFR; IDDM10
Application :
WB, IHC, ICC/IF
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
-
Background
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]
-
Immunogen
A synthetic peptide of human IL-2 Receptor alpha
-
Gene ID
3559
16184
25704
-
Swiss Prot
P01589
P01590
P26897
-
Synonyms
p55; CD25; IL2R; IMD41; TCGFR; IDDM10
-
Reactivity
Human, Mouse, Rat
-
Application
WB, IHC, ICC/IF
-
Recommended dilution
WB: 1:1000
IHC: 1:200
ICC/IF: 1:200
-
Calculated MW
31 kDa
-
Observed MW
40-80 kDa
-
Host species
Rabbit
-
Clonality
Polyclonal
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
20μL
598
-
50μL
998
-
100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号