Phospho-PKC zeta (Thr560) Rabbit pAb - diagbio | 戴格生物

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Phospho-PKC zeta (Thr560) Rabbit pAb

db4725

Product Name : Phospho-PKC zeta (Thr560) Rabbit pAb

Cat.No.: db4725

Synonyms : PKC2; PKC-ZETA

Application : WB

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Thr560 of human PKC zeta
Gene ID 5590
Swiss Prot Q05513
Synonyms PKC2; PKC-ZETA
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000-1:5000
Calculated MW 68 kDa
Observed MW 68 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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