Product Name :
CD45 Rabbit pAb
Cat.No.:
db4592
Synonyms :
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
Application :
WB, IHC, ICC/IF, FC
Reactivity :
Human
Host species :
Rabbit
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
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Immunogen
A synthetic peptide of human CD45
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Gene ID
5788
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Swiss Prot
P08575
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Synonyms
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180
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Reactivity
Human
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:2000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
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Calculated MW
147 kDa
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Observed MW
180-240 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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