Myc Tag Rabbit pAb - diagbio | 戴格生物

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Myc Tag Rabbit pAb

db457

Product Name : Myc Tag Rabbit pAb

Cat.No.: db457

Synonyms : MRTL; MYCC; c-Myc; bHLHe39

Application : WB, ICC/IF, FC

Reactivity : Other

Host species : Rabbit

Background This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of Myc tag
Swiss Prot P01106
Synonyms MRTL; MYCC; c-Myc; bHLHe39
Reactivity Other
Application WB, ICC/IF, FC
Recommended dilution WB: 1:1000
ICC/IF: 1:50
FC: 1:20
Calculated MW 49 kDa
Observed MW According to the fused protein
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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