CD63 Rabbit pAb - diagbio | 戴格生物

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CD63 Rabbit pAb

db4428

Product Name : CD63 Rabbit pAb

Cat.No.: db4428

Synonyms : ME491; C75951; Tspan30

Application : WB, IHC, ICC/IF

Reactivity : Mouse

Host species : Rabbit

Background Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
Immunogen A synthetic peptide of mouse CD63
Gene ID 12512
Swiss Prot P41731
Synonyms ME491; C75951; Tspan30
Reactivity Mouse
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
Calculated MW 26 kDa
Observed MW 40-70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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