CD8 alpha Rabbit pAb - diagbio | 戴格生物

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CD8 alpha Rabbit pAb

db4210

Product Name : CD8 alpha Rabbit pAb

Cat.No.: db4210

Synonyms : Ly-2; Ly-B; Ly-35; Lyt-2; BB154331

Application : WB, IHC, FC, IP

Reactivity : Mouse

Host species : Rabbit

Background Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Immunogen Recombinant protein of mouse CD8 alpha
Gene ID 12525
Swiss Prot P01731
Synonyms Ly-2; Ly-B; Ly-35; Lyt-2; BB154331
Reactivity Mouse
Application WB, IHC, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:500
FC: 1:100
IP: 1:20
Calculated MW 28 kDa
Observed MW 35-42 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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