IL-1 beta Rabbit pAb - diagbio | 戴格生物

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IL-1 beta Rabbit pAb

db4188

Datasheet

Product Name : IL-1 beta Rabbit pAb

Cat.No.: db4188

Synonyms : IL-1; IL1F2; IL1-BETA

Application : WB, IP

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human IL1 beta
Gene ID 3553
Swiss Prot P01584
Synonyms IL-1; IL1F2; IL1-BETA
Reactivity Human
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 31 kDa
Observed MW 17,31 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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