Product Name :
TGF beta 1 Rabbit pAb
Cat.No.:
db4124
Synonyms :
CED; LAP; DPD1; TGFB; TGFbeta
Application :
WB, IHC
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
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Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
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Immunogen
Recombinant protein of human TGF beta 1
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Gene ID
7040
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Swiss Prot
P04202
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Synonyms
CED; LAP; DPD1; TGFB; TGFbeta
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC
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Recommended dilution
WB: 1:1000
IHC: 1:100
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Calculated MW
44 kDa
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Observed MW
44 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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