Insulin Rabbit pAb - diagbio | 戴格生物

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Insulin Rabbit pAb

db412

Product Name : Insulin Rabbit pAb

Cat.No.: db412

Synonyms : IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10

Application : WB, IHC, ICC/IF

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Background After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Immunogen Recombinant protein of human Insulin
Gene ID 3630
Swiss Prot P01308
Synonyms IDDM; ILPR; IRDN; IDDM1; IDDM2; MODY10
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:20-1:5000
ICC/IF: 1:50
Calculated MW 12 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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