Cleaved Caspase-3 Rabbit pAb - diagbio | 戴格生物

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Cleaved Caspase-3 Rabbit pAb

db386

Product Name : Cleaved Caspase-3 Rabbit pAb

Cat.No.: db386

Synonyms : CPP32; SCA-1; CPP32B

Application : WB, ICC/IF

Reactivity : Human

Host species : Rabbit

Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human active Caspase-3
Gene ID 836
Swiss Prot P42574
Synonyms CPP32; SCA-1; CPP32B
Reactivity Human
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:100
Calculated MW 32 kDa
Observed MW 17 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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